7-thiaprostaglandins and method of production thereof

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 405/00 (2006.01) C07D 207/337 (2006.01) C07D 213/55 (2006.01) C07D 307/54 (2006.01) C07D 309/12 (2006.01) C07D 333/74 (2006.01) C07F 7/18 (2006.01) C07F 7/22 (2006.01)

Patent

CA 2158350

7-Thiaprostaglandins represented by general formula (I), enantiomers thereof, and mixtures thereof, inhibiting cell migration caused by chemokives such as monocyte migration factor MCP-1/MCAF and serving as a remedy for arteriosclerosis, diabetic angiopathy, and the like.

L'invention se rapporte à des 7-thiaprostaglandines représentées par la formule générale (I), à des énantiomères de ces substances, et à leurs mélanges, qui inhibent la migration cellulaire provoquée par des chémokives tels que le facteur de migration monocytaire MCP-1/MCAF, et qui servent de remède contre l'artériosclérose, l'angiopathie diabétique et des affections similaires.

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