7h-pyrrolopyrimidine derivatives

Details 7h-pyrrolopyrimidine derivatives 7h-pyrrolopyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2553889

The invention relates to 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula (I), wherein the symbols and substituents are as defined in the description, to processes for the preparation thereof, to pharmaceutical compositions comprising such derivatives and to the use of such derivatives - alone or in combination with one or more other pharmaceutically active compounds - for the preparation of pharmaceutical compositions for the treatment especially of a proliferative disease, such as a tumour.

La présente invention concerne des dérivés 7H-pyrrolo[2,3-d]pyrimidine représentés par la formule (I) dans laquelle, les symboles et les substituants sont tels que définis dans les descriptions, des processus de préparation de ces dérivés, des compositions pharmaceutiques comprenant ces dérivés et l'utilisation de ces dérivés, seuls ou en combinaison avec un ou plusieurs composés pharmaceutiquement actifs, pour la préparation de compositions pharmaceutiques destinées en particulier au traitement d'une maladie proliférative, telle qu'une tumeur.

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