8-[3-amino-piperidin-1-yl]-xanthine, the production thereof...

Details 8-[3-amino-piperidin-1-yl]-xanthine, the production thereof... 8-[3-amino-piperidin-1-yl]-xanthine, the production thereof...

C - Chemistry, Metallurgy

07

D

C07D 473/04 (2006.01) A61K 31/437 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2555050

The invention relates to substituted xanthines of general formula (I), wherein R is such as defined in claim 1, and to the tautomers, stereoisomers, mixtures and the salts thereof, said products exhibiting precious pharmacological properties, in particular an inhibiting effect on a dipeptidylpeptidasa-IV (DPP-IV) enzyme activity.

L'invention concerne des xanthines substituées, de formule générale (I), dans laquelle R est tel que défini dans la revendication 1, ainsi que leurs tautomères, leurs stéréoisomères, leurs mélanges et leurs sels, ces produits présentant des propriétés pharmacologiques précieuses, en particulier, un effet inhibiteur sur l'activité de l'enzyme dipeptidylpeptidase-IV (DPP-IV).

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