8-[3-amino-piperidin-1-yl]-xanthines, the production...

Details 8-[3-amino-piperidin-1-yl]-xanthines, the production... 8-[3-amino-piperidin-1-yl]-xanthines, the production...

C - Chemistry, Metallurgy

07

D

C07D 473/06 (2006.01) A61K 31/522 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2556064

The invention relates to substituted xanthines of general formula (I) wherein R1 and R2 have the designations cited in patent claims 1 to 3. The invention also relates to the tautomers, stereoisomers, mixtures and salts of said xanthines, exhibiting valuable pharmacological properties, especially an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP- IV).

La présente invention concerne des xanthines substituées de formule générale (I), dans laquelle R?1¿ et R?2¿ sont tels que définis dans les revendications 1 à 3, leurs tautomères, leurs stéréoisomères, leurs mélanges et leurs sels, qui présentent de précieuses propriétés pharmacologiques, notamment un effet d'inhibition de l'activité de l'enzyme dipeptidylpeptidase-IV (DPP-IV).

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