8,8-disubstituted-6-methylergolines and related compounds

C - Chemistry – Metallurgy – 07 – D

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260/206.1

C07D 457/04 (2006.01) C07D 457/02 (2006.01)

Patent

CA 1064918

Abstract of the Disclosure A process for preparing novel 8,8-disubstituted- 6-methylergolines and 9-ergolenes is described herein. This process comprises alkylating an ester of lysergic or isolysergic acid or of dihydrolysergic or dihydroisolysergic acid. These novel compounds are useful as prolactin in- hibitors.

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