8,9-annelated-ß-carbolines and 8,9-annelated-3,...

Details 8,9-annelated-ß-carbolines and 8,9-annelated-3,... 8,9-annelated-ß-carbolines and 8,9-annelated-3,...

C - Chemistry, Metallurgy

07

D

167/208, 260/241

C07D 471/14 (2006.01) A61K 31/47 (2006.01) C07D 471/16 (2006.01) C07D 513/14 (2006.01) C07D 513/16 (2006.01)

Patent

CA 1338190

The invention relates to a group of new 8,9-annelated-.beta.- carbolines and 8,9-annelated-3,4-dihydro-.beta.-carbolines having interesting fibrinolytic properties. In particular the compounds can be used as orally active fibrinolytics. The compounds have the general formulae 1 and 2 Image Image (1) (2) wherein R2 + R3 together with the carbon atom and the nitrogen atom to which they are bound and the intermediate carbon atom constitute a heterocyclic group consisting of 5-10 ring atoms.

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