8-alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)...

C - Chemistry – Metallurgy – 07 – D

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260/242.5

C07D 471/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 1074793

A B S T R A C T Valuable antibacterial 8-alkyl-5-oxo-5,8- dihydro-pyrido(2,3-d) pyrimidine-6-carboxylic acids, some of which are new compounds, are made from corresponding pyrimidines by a process involving condensation with an amino-ester, cyclization, halogenation, dehydrohalogenation, and saponification.

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