8.alpha.-acylaminoergolines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 457/12 (2006.01) C07D 457/04 (2006.01) C07D 457/06 (2006.01)

Patent

CA 1245640

ABSTRACT Compounds of formula I Image (1) wherein R1 is hydrogen or C1-4alkyl, R2 is hydrogen, chlorine, bromine or methyl, R3 is C1-5alkyl or C3-5alkenyl and R4 is C3-7alkyl; C3-7cycloalkyl; adamantyl; or optionally substi- tuted phenyl, having valuable pharmaceutical, and in parti- cular LH- and PRL-secretion inhibiting as well as neuroleptic activity.

471859

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