8-aza-bicyclo[3.2.1]octane nmda/nr2b antagonists

Details 8-aza-bicyclo[3.2.1]octane nmda/nr2b antagonists 8-aza-bicyclo[3.2.1]octane nmda/nr2b antagonists

C - Chemistry, Metallurgy

07

D

C07D 471/08 (2006.01) A61K 31/46 (2006.01) A61P 29/02 (2006.01) C07D 401/06 (2006.01) C07D 451/02 (2006.01)

Patent

CA 2388171

Novel 3-substituted 8-aza-bicyclo[3.2.1]octanes (commonly known as "tropanes") substituted in the 8-position are effective as NMDA NR2B antagonists useful for relieving pain.

La présente invention concerne de nouveaux 3-substitué 8-aza-bicyclo[3.2.1]octanes (communément connus sous le nom de <= tropanes >=), substitués en position 8, qui sont efficaces en tant qu'antagonistes NMDA NR2B, utiles pour soulager la douleur.

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