8-azaprostaglandin carbonate and thiocarbonate analogs as...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/26 (2006.01) A61K 31/4015 (2006.01) A61P 27/06 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2528006

The present invention provides a compound represented by the general formula (I), wherein A, Ar, X, Z, n, x, y, R, and R3 are as defined in the specification. The compounds are useful in the treatment of glaucoma and other prostalandin-related diseases.

L'invention concerne un composé de formule générale (I) dans laquelle A, AR, X, Z, n, x, y, R et R?3¿ ont la signification indiquée dans la description. Ces composés sont utiles dans le traitement des glaucomes et d'autres maladies associées à la prostaglandine.

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