8-chloro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidyliden]...

Details 8-chloro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidyliden]... 8-chloro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidyliden]...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/445 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2096318

The present invention relates to 8-chloro-11-[1-[(5- methyl-3-pyridyl)methyl]-4-piperidyliden]-6,11-dihydro-5H- benzo[5,6]cyclo-hepta[1,2-b]pyridine (4) of the formula (see fig. I) to a process for its preparation and to pharmaceutical compositions containing it. This compound is a dual PAF antagonist and antihistamine.

L'invention porte sur une 8-chloro-11-¢1-¢(5- méthyl-3-pyridyl)méthyl!-4-pipéridylidène!- 6,11-dihydro-5H- benzo¢5,6!cyclohepta¢1,2-b!pyridine (4) de formule (voir fig. I), sur une méthode pour la préparer et sur des compositions pharmaceutiques à base de ce composé, qui est à la fois un antagoniste du PAF et un antihistaminique.

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