8-cyano-6,7-dihydro-5-methyl-1-oxo-1h,5h- benzo¬ij|...

C - Chemistry – Metallurgy – 07 – D

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C07D 455/04 (2006.01) A01N 43/90 (2006.01) C07C 205/57 (2006.01) C07C 205/58 (2006.01) C07D 215/38 (2006.01) C07D 215/48 (2006.01)

Patent

CA 1217493

- 1 - Abstract of the Disclosure The compounds 8-cyano-6,7-dihydro-5-methyl-1-oxo 1H,5H-benzo[ij]quinolizine-2-carboxylic acid and 8-cyano- 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo[ij]quinoli- zine-2-carboxylic acid are disclosed as potent antimicro- bial agents. Pharmaceutically-acceptable carboxylate salts, esters, acyl chlorides, amides and alkylaminoalkyl ester salts of the acids are also disclosed.

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