8-ene-19, 11.bet.beta.-bridged steroids, their preparation...

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 53/00 (2006.01) A61K 31/56 (2006.01) C07J 63/00 (2006.01)

Patent

CA 2097079

ABSTRACT OF THE DISCLOSURE Described are 8-ene-19, 11.beta.-bridged steroids of general formula (I) which have a new structural feature in the form of a double bond between the 8 position and the 9 position. Also described is a method of preparing them. The substituents R1, R4-Y, R4'-Y', X and Z are defined in the specification. The new compounds have, in particular, a strong anti-progastational action and are suitable for the preparation of pharmaceutical formulations.

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