8-methoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones and...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 513/04 (2006.01) A61K 31/4365 (2006.01) A61P 33/00 (2006.01)

Patent

CA 2616768

The invention provides compound and salts of Formula (I) and (II), disclosed herein, which includes compounds of Formula (A) and Formula (B) such compounds possess useful antimicrobial activity. The variables R2, R3, R5, R6, R7, and R9 shown in Formula A and B are defined herein. Certain compounds of Formula (I) and Formula (II) disclosed herein are potent and/ or selective inhibitors of bacterial DNA synthesis and bacterial replication. The invention also provides antimicrobial compositions, including pharmaceutical compositions, containing one or more compounds of Formula (I) or Formula (II) and one or more carriers, excipients, or diluents. Such compositions may contain a compound of Formula (I) or Formula (II) as the only active agent or may contain a combination of a compound of Formula I or Formula II and one or more other active agents. The invention also provides methods for treating microbial infections in animals.

L'invention concerne un composé et des sels représentés par les formules (I) et (II) décrites ici, qui incluent des composés de formule (A) et de formule (B) , lesdits composés possédant une activité antimicrobienne utile. Les variables R2, R3, R5, R6, R7, et R9 qui apparaissent dans les formules A et B sont définies ici. Certains composés de la formule (I) et de la formule (II) décrits ici sont des inhibiteurs puissants et/ou sélectifs de la synthèse de l'ADN bactérien et de la réplication bactérienne. L'invention concerne également des compositions antimicrobiennes, y compris des compositions pharmaceutiques contenant un ou plusieurs composés de formule (I) ou de formule (II) et un ou plusieurs vecteurs, excipients ou diluants. De telles compositions peuvent contenir un composé de formule (I) ou de formule (II) comme seul principe actif, ou peuvent contenir une combinaison de composés de formule (I) ou de formule (II) et un ou plusieurs autres principes actifs. De plus, l'invention concerne des procédés de traitement des infections microbiennes chez l'animal.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

8-methoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 8-methoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 8-methoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1592834

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.