8-phenyl-6,9-dihydro-¬1,2,4|triazolo¬3,4-i|purin-5-one...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/14 (2006.01) A61K 31/522 (2006.01) A61P 1/00 (2006.01) A61P 9/00 (2006.01) A61P 15/00 (2006.01) C07D 235/00 (2006.01) C07D 239/00 (2006.01) C07D 249/00 (2006.01) C07D 473/04 (2006.01) C07D 473/06 (2006.01) C07D 473/18 (2006.01) C07D 473/22 (2006.01)

Patent

CA 2380181

8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-<i>i</i>]purin-5-one derivatives of formula (I) or a pharmaceutically acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use as PDE 5 inhibitors.

L'invention concerne des dérivés de 8-phényl-6,9-dihydro-[1,2,4]triazolo[3,4-<i>i</i>]purine-5 one de formule(I) ou un sel pharmaceutiquement acceptable de ces produits, des procédés de préparation de ces derniers, des compositions pharmaceutiques les contenant, ainsi que leur utilisation en tant qu'inhibiteurs PDE 5.

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