8-piperazinyl-1, 7-naphthyridine derivative

Details 8-piperazinyl-1, 7-naphthyridine derivative 8-piperazinyl-1, 7-naphthyridine derivative

C - Chemistry, Metallurgy

07

D

260/266.3

C07D 471/04 (2006.01)

Patent

CA 1300630

ABSTRACT OF THE DISCLOSURE An 8-piperazinyl-1,7-naphthyridine derivative represented by the following formula (I): Image (I) in which R represents a hydrogen atom; a formyl group; a lower alkanoyl group; a benzoyl group which may have one or more halogen atom, nitro group, or lower alkoxy group substituents; a furanylcarbonyl group; a pyridylcarbonyl group; a phenyl group which has one or more halogen atom, lower alkoxyl group, or trifluoromethyl group substituents; a pyridyl group; a benzyl group; a diphenylmethyl group, or a benzenesulfonyl group which may have one or more lower alkyl group or halogen atom substituents; or a pharmaceutically acceptable salt thereof. The compound has excellent antiinflammatory, antiarrhythmic and cardiotonic effects, and thus is useful as an antiinflammatory drug and a medicine for circulatory organs.

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