8-thiomethylergolines

C - Chemistry – Metallurgy – 07 – D

Patent

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260/206.7

C07D 457/02 (2006.01)

Patent

CA 1071623

Abstract of the Disclosure 8-Thiomethylergolines, which are useful as pro- lactin inhibitors, are described hereinO These compounds are prepared by reacting via nucleophilic displacement an ester of a D-6-methyl-8-hydroxymethylergoline or of a 9,10-didehydroergoline with salts of thio- phenol, a thioalkanoic acid, or an alkylthiol.

228332

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