85kda neisserial antigen

Details 85kda neisserial antigen 85kda neisserial antigen

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 31/711 (2006.01) A61K 39/095 (2006.01) A61K 39/40 (2006.01) C07K 14/22 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2390344

An 85kDa antigen from Neisseria meningitidis and Neisseria gonorrhoeae has been cloned, sequenced and expressed. The antigen is common to diverse strains, serogroups and serotypes of N.meningitidis, and also to N.gonorrhoeae, N.polysaccharia and N.lactamica. The protein sequences of N.meningitids (serogroups A and B) and N.gonorrhoeae are highly homologous.

L'invention concerne un antigène de 85kDa provenant de Neisseria meningitidis et de Neisseria gonorrhoeae, cloné, séquencé et exprimé. Cet antigène est commun à plusieurs souches, sérogroupes et sérotypes de N.meningitidis, mais aussi àN.gonorrhoeae, N.polysaccharia et N.lactamica. Les séquences protéiques de N.meningitidis (sérogroupes A et B) et de N.gonorrhoeae sont fortement homologues.

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