8a-aza-8a-homoertyhromycin cyclic lactams

Details 8a-aza-8a-homoertyhromycin cyclic lactams 8a-aza-8a-homoertyhromycin cyclic lactams

C - Chemistry, Metallurgy

07

H

C07H 17/00 (2006.01) A61K 31/70 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2064985

186/FPG84 18357IB TITLE OF THE INVENTION 8a-AZA-8a-HOMOERYTHROMYCIN LACTAMS ABSTRACT OF THE INVENTION Lactams of the general structural formula: Image wherein R is hydrogen, linear straight or branched chain alkyl of 1 to 10 carbon atoms, linear straight or branched chain alkenyl of 2 to 10 carbon atoms, with one or more degrees of unsaturation, cycloalkyl of up to 10 carbon atoms, or cycloalkenyl of up to 10 carbon atoms with one or more degrees of unsaturation; these compounds are macrolides useful as antibiotics and as intermediates for the synthesis of other macrolide antibiotics.

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