8a-aza-8a-homoerythromycin cyclic iminoethers

C - Chemistry – Metallurgy – 07 – H

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C07H 17/00 (2006.01) A61K 31/70 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2065674

190/FGP89 191/FGP90 18300IA TITLE OF THE INVENTION 8a-AZA-8a-HOMOERYTHROMYCIN CYCLIC IMINOETHERS ABSTRACT OF THE INVENTION Cyclic iminoethers of the general structural formula wherein one of the R groups is hydrogen and the other R group represents a bond between the oxygen atom at C-6 or C-12 and the imino carbon at C-9: Image Image and These compounds axe macrolides useful as antibiotics and as intermediates for the synthesis of other macrolide antibiotics.

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