8h-indeno ¬ 2,1-b| thiophen-2-oxaminic acids and esters thereof

C - Chemistry – Metallurgy – 07 – D

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260/328.3

C07D 333/50 (2006.01) C07D 333/74 (2006.01) C07D 333/78 (2006.01) C07D 333/80 (2006.01)

Patent

CA 1106850

Case 100-4738 8H-INDENO-[2,1-b] THIOPHEN-2-OXAMINIC ACIDS AND ESTERS THEREOF Abstract of the Disclosure: The present invention provides compounds of formula, Image wherein n is from 0 to 4, m is from 0 to 4, whereby n + m is at least 1 and not more than 4, each of R1, R2, R3 and R4 may independently be, for example, hydro- gen, alkyl or alkoxy, R5 may, for example, be nitrile or carbamoyl and R6 is hydrogen and, when n is 2 and m is 0, one of R6 can be alkyl of 1 to 4 carbon atoms, which compounds possess pharmaceutical, for example anti- allergic, activity.

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