9-(2-0-acyl-.beta.-d-arabinofuranosyl) adenine compounds and...

Details 9-(2-0-acyl-.beta.-d-arabinofuranosyl) adenine compounds and... 9-(2-0-acyl-.beta.-d-arabinofuranosyl) adenine compounds and...

A - Human Necessities

61

K

195/89

A61K 31/52 (2006.01) C07H 19/16 (2006.01) C07H 23/00 (2006.01) C12P 19/40 (2006.01)

Patent

CA 1073385

Abstract of the Disclosure: 9-(2-0-Acyl-.beta.-D-arabinofuranosyl)adenine compounds and their production by enzymatic removal of the 3-O-acyl and 5-O-acyl groups of a 9-(2,3-di-)-acyl-.beta.-D- arabinofuranosyl)adenine compound or a 9-(2,3,5,-tri-)-acyl-.beta.- D-arabinofuranosyl)adenine compound. The monoester compounds are useful as antiviral agents. The compounds are water- soluble and lipophilic, thereby being adaptable to a wide variety of pharmaceutical formulations. - 1 -

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