9-(2-(hydroxymethyl)cycloalkylmethyl)guanines

Details 9-(2-(hydroxymethyl)cycloalkylmethyl)guanines 9-(2-(hydroxymethyl)cycloalkylmethyl)guanines

C - Chemistry, Metallurgy

07

D

167/220, 260/242

C07D 473/18 (2006.01) A61K 31/52 (2006.01) C07D 473/00 (2006.01)

Patent

CA 1276635

TITLE OF INVENTION 9-[2-(HYDROXYMETHYL)CYCLOALKYLMETHYL]GUANINES ABSTRACT OF DISCLOSURE 9-[2-(Hydroxymethyl)cycloalkylmethyl]guanines which are herpes simplex viral thymidine kinase inhibitors, their acyl derivatives, their phosphate derivatives and their pharmaceutically-acceptable salts; pharmaceutical formulations containing these compounds; the treatment of DNA viral, particularly herpes viral, infections with these compounds; methods of preparing these compounds; and novel intermediates useful in their preparation.

566440

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