9-(3-o-acyl-.beta.-d-arabinofuranosyl) adenine compounds,...

C - Chemistry – Metallurgy – 07 – H

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C07H 23/00 (2006.01) C07H 19/16 (2006.01)

Patent

CA 1062704

Application for Letters Patent on an Invention Entitled: "9-(3-0-ACYL-.beta.-D-ARABINOFURANOSYL)ADENINE COMPOUNDS, 9-(2,3-DI-O-ACYL-.beta.-D-ARABINOFURANOSYL)- ADEINE COMPOUNDS, AND METHOD FOR THEIR PRODUCTION" Abstract of the Disclosure: 9-(3-O-Acyl-.beta.-D-arabinofuranosyl)adenine compounds, 9-(2y3-di-O-acyl-.beta.-D-arabinofuranosyl)adenine compounds, and their production by reacting in each case the corresponding 5-silyl ether derivative with a tetraalkyl- ammonium fluoride. The compounds are useful as antiviral agents. The compounds are water-soluble and lipophilic, thereby being adaptable to a wide variety of pharmaceutical formulations. SUMMARY AND DETAILED DESCRIPTION: - 1 -

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