9-alkylamino-1-nitroacridine derivatives

Details 9-alkylamino-1-nitroacridine derivatives 9-alkylamino-1-nitroacridine derivatives

C - Chemistry, Metallurgy

07

D

C07D 219/12 (2006.01) A61K 31/473 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01) C07D 219/04 (2006.01) C07D 219/06 (2006.01) C07D 219/10 (2006.01)

Patent

CA 2400394

The invention is directed to novel 9-hydroxyalkylamino-, 9-alkoxyalkylamino-1- nitroacridine and 9-acyloxyalkylamino-1-nitroacridine compounds having the following structural formula: (see above formula) Methods of preparation, pharmaceutical compositions comprising said compounds and their medical use (e.g., as anticancer agents) are also encompassed by this invention.

L'invention concerne de nouveaux dérivés de 9-hydroxyalkylamino,9-alcoxyalkylamino-1-nitroacridine. L'invention concerne également des méthodes de préparation desdits dérivés, des compositions pharmaceutiques renfermant lesdits dérivés et leur utilisation médicale.

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