9.alpha.-dehalogenation of steroids using tin or lead

C - Chemistry – Metallurgy – 07 – J

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260/361, 260/59,

C07J 75/00 (2006.01) C07C 1/26 (2006.01) C07C 5/00 (2006.01) C07D 307/93 (2006.01) C07D 307/935 (2006.01) C07J 5/00 (2006.01)

Patent

CA 2025670

2025670 9009394 PCTABS00001 The process of the present invention is a process for the preparation of an 11-oxygenated steroid of formula (II) which comprises (1) contacting a 9.alpha.-halo steroid of formula (I) with a metal selected from the group consisting of tin (0), a tin (II) salt, lead (0) or a lead (II) salt, a hydrogen atom donor and an initiator.

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