9-deoxo-9(z)-hydroxyiminoerythromycin a and o-derivatives...

Details 9-deoxo-9(z)-hydroxyiminoerythromycin a and o-derivatives... 9-deoxo-9(z)-hydroxyiminoerythromycin a and o-derivatives...

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/71 (1990.01)

Patent

CA 2062932

24/FPG13 18301 TITLE OF THE INVENTION 9-DEOXO-9(Z)-HYDROXYIMINOERYTHROMYCIN A AND O-DERIVATIVES THEREOF ABSTRACT OF THE INVENTION The Z-isomer of 9-Deoxo-9-hydroxy- iminoerythromycin A. The Z-isomer is useful as an antibiotic and as an intermediate for the synthesis of other macrolide antibiotics. The Z-isomer and its O-derivatives have the following structure: Image (II) wherein R is hydrogen, C1-10 alkyl or arylsulfonyl.

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