9-deoxy-6,9-epoxyprostaglandins

Details 9-deoxy-6,9-epoxyprostaglandins 9-deoxy-6,9-epoxyprostaglandins

C - Chemistry, Metallurgy

07

D

260/235.01

C07D 307/935 (2006.01) C07C 405/00 (2006.01) C07D 307/937 (2006.01) C07D 311/94 (2006.01) C07D 313/00 (2006.01)

Patent

CA 1160627

2871A-1-F ABSTRACT OF THE DISCLOSURE Prostaglandin (PG1) derivatives having (1) a 9-deoxy- 6,9-epoxy feature as well as 5-iodo, 5,6-didehydro, or 6- hemiketal or (2) a 6-keto feature are disclosed; including processes for preparing them and the appropriate inter- mediates; said derivatives having pharmacological activity, A typical 5-iodo compound is 9-deoxy-6,9-epoxy-5-iodo- PGF 1.alpha. represented by the formula: Image -1-

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