9-oxo-13,18-prostadienoic acid derivatives and process for...

C - Chemistry – Metallurgy – 07 – C

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260/235.07

C07C 405/00 (2006.01) C07C 57/03 (2006.01) C07C 57/13 (2006.01) C07F 7/18 (2006.01) C07F 9/40 (2006.01)

Patent

CA 1205469

Abstract 9-oxo-13,18-prostadienoic acid derivatives and process for their preparation A (13E)-(8R,11R,12R)-11-15-dihydroxy-9-oxo-13,18- prostadienoic acid which is substituted at the 16-position by one or two methyl groups and at the 19-position by one methyl group, or a salt thereof, is provided by the present invention. Such prostenoic acid derivatives have been found to exhibit such a therapeutic effectiveness that the amount of active substance administered to a patient can be reduced significantly in comparison with commercial preparations already available.

396022

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