9-(phosphonylmethoxyalkyl)adenines, the method of...

Details 9-(phosphonylmethoxyalkyl)adenines, the method of... 9-(phosphonylmethoxyalkyl)adenines, the method of...

C - Chemistry, Metallurgy

07

F

260/242.3

C07F 9/547 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 1295614

ABSTRACT OF THE DISCLOSURE: The invention relates to 9-(phosphonylmethoxyalkyl) adenines of the general formula I Image (I) wherein R1 is a hydrogen atom, an alkyl group containing one to three carbon atoms, or a hydroxymethyl group, R2 is a methylene, ethylene, propylene, ethylidene, methoxyethylidene, benzyloxyethylidene, tetrahydropyran-2-yloxyethylidene, (1-ethoxy- ethoxy)ethylene or 1,2-O-isopropylidene-1,2-dihydroxypropylene group. The invention also relates to the salts of these compounds, a method for preparing them and their use. These compounds of the general formula I exhibit biological effects (e.g. antiviral) or can be converted into compounds with such effects.

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