9-substituted minocycline compounds

Details 9-substituted minocycline compounds 9-substituted minocycline compounds

C - Chemistry, Metallurgy

07

C

C07C 237/26 (2006.01) A61K 31/65 (2006.01) C07C 255/59 (2006.01) C07C 271/22 (2006.01) C07C 271/28 (2006.01) C07C 271/30 (2006.01) C07C 271/58 (2006.01) C07C 275/34 (2006.01) C07C 275/38 (2006.01) C07C 275/40 (2006.01) C07C 275/42 (2006.01) C07C 275/50 (2006.01) C07C 275/54 (2006.01) C07C 311/06 (2006.01) C07C 311/21 (2006.01) C07C 333/08 (2006.01) C07C 335/22 (2006.01) C07C 381/10 (2006.01) C07D 295/155 (2006.01) C07F 9/40 (2006.01)

Patent

CA 2415178

The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocyline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

La présente invention concerne, au moins en partie, des composés de minocycline 9- substitués. Ces composés de minocycline peuvent être utilisés dans le traitement de nombreux états réagissant à des composés de la tétracycline, tels que des infections bactériennes et des tumeurs ainsi que pour d'autres applications connues des composés de la minocycline et de la tétracycline en général, par exemple pour le blocage l'efflux de la tétracycline et la modulation de l'expression génique.

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