99mtc (iii) myocardial imaging agents that are effective in...

C - Chemistry – Metallurgy – 07 – F

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C07F 13/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 2051699

2051699 9014106 PCTABS00002 A myocardial imaging agent for humans is a technetium(III) complex ligated in the planar positions by a tetradentate ligand such as (acac)2en and in the axial positions by an ether containing phosphine ligand such as tris(3-methoxy-1-propyl)-phosphine. The agent exhibits extremely rapid blood clearance after injection into a human (as shown in the figures) and has a sufficiently high heart/liver and heart/lung ratios to provide effective myocardial images.

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