9h-imidazo[1,2-a]benzimidazole-3-acetamide derivatives,...

Details 9h-imidazo[1,2-a]benzimidazole-3-acetamide derivatives,... 9h-imidazo[1,2-a]benzimidazole-3-acetamide derivatives,...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/395 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2113490

- 57 - ABSTRACT 9H-IMIDAZO[1,2-a]BENZIMIDAZOLE-3-ACETAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Compound corresponding to the formula: (I) Image in which X represents one or more of hydrogen, halogen, alkyl, trifluoromethyl, alkoxy, alkylthio, methylsulphonyl, cyano, ethoxycarbonyl, aminocarbonyl and carboxy, Y represents one or more of hydrogen, halogens, alkyl, trifluoromethyl, methoxy and trifluoromethoxy, R1 represents hydrogen, alkyl, phenylmethyl, 2-phenylethyl, acetyl or alkoxycarbonyl, R2 and R3 each represent hydrogen, alkyl which is optionally substituted, prop-2-enyl, prop-2- ynyl, phenyl, 1-(phenylmethyl)piperidin-4-yl, or 1- [(cyclohexen-1-yl)methyl]piperidin-4-yl, or alternatively R2 and R3 form, with the nitrogen atom carrying them, an optionally substituted heterocycle. These compounds are useful as hypnotio, anxiolytic and anticonvulsant agents.

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