A baclofen solution for low-volume therapeutic delivery

A - Human Necessities – 61 – K

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A61K 31/197 (2006.01)

Patent

CA 2721134

A high concentration baclofen solution is provided suitable for therapeutic use in a medical setting. A high concentration solution of baclofen in multivalent physiological ion solution such as artificial cerebrospinal fluid is provided with concentrations of baclofen of 10 mg/ml. Artificial cerebrospinal fluid is particularly advantageous as a baclofen solvent. A medical package is also provided for baclofen delivery to patients suffering from spasticity.

L'invention concerne une solution de baclofène à concentration élevée pouvant être utilisée à des fins thérapeutiques dans un environnement médicalisé. On obtient une solution de baclofène à concentration élevée dans une solution ionique physiologique multivalente telle qu'un liquide céphalorachidien, avec des concentrations de baclofène de 10 mg/ml. Un liquide céphalorachidien artificiel est particulièrement approprié comme solvant pour le baclofène. L'invention concerne également un conditionnement médical pour l'administration de baclofène à des patients souffrant de spasticité.

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