A barrier cream comprising hexamethylenetetramine or...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/22 (2006.01) A61K 31/02 (2006.01) A62D 5/00 (2006.01) C07D 487/12 (2006.01) C07D 487/18 (2006.01)

Patent

CA 2253459

The present invention relates to skin protection agents, in particular to topical compositions which can prevent the passage of toxic chemicals through the skin, such as barrier creams. Formulations may contain hexamethylene tetramine or derivatives or analogues thereof, which react with alkylating agents such as sulphur mustard, and which are suitable for formulation into topical compositions. The formulations additionally may contain perfluorinated polymeric compounds which are effective barrier compounds for a range of toxic chemicals.

Agents de protection de la peau, en particulier compositions chimiques topiques qui peuvent empêcher le passage de produits chimiques à travers la peau, tels que des crèmes isolantes. Lesdites compositions peuvent contenir de l'hexaméthylène tétramine ou des dérivés ou analogues de ladite substance, qui réagissent avec des agents alkylants tels que le sulfure de la moutarde, et qui sont appropriés pour entrer dans la formulation desdites compositions topiques. Ces compositions peuvent en outre contenir des composés polymères perfluorés qui constituent des composés barrières efficaces pour toute une gamme de produits chimiques toxiques.

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