A basal cell carcinoma tumor suppressor gene

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2266408

This invention provides for a tumor suppressor gene inactivation of which is a causal factor in nevoid basal cell carcinoma syndrome and various sporadic basal cell carcinomas. The NBCCS gene is a homologue of the Drosophila patched (ptc) gene.

L'invention concerne un gène suppresseur de tumeur dont l'inactivation est un facteur déterminant dans le syndrome du carcinome basocellulaire angiomateux (NBCCS) et dans divers carcinomes basocellulaires sporadiques. Le gène NBCCS est un homologue du gène de la drosophile Drosophila patched (ptc).

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