A .beta.1-6 n-acetylglucosaminyltransferase and encoding dna

Details A .beta.1-6 n-acetylglucosaminyltransferase and encoding dna A .beta.1-6 n-acetylglucosaminyltransferase and encoding dna

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C07K 14/705 (2006.01) C07K 14/725 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12N 15/12 (2006.01) C12N 15/64 (2006.01)

Patent

CA 2145657

The present invention provides a novel .beta.1->6 N-acetylglucosaminyltransferase, which forms core 2 oligosaccharide struc- tures in ?-glycans, and a novel acceptor molecule, leukosialin, CD43, for core 2 .beta.1-> 6 N-acetylglucosaminyltransferase activity. The amino acid sequences and nucleic acid sequences encoding these molecules, as well as active fragments thereof, also are dis- closed. A method for isolating nucleic acid sequences encoding proteins having enzymatic activity is disclosed, using CHO cells that support replication of plasmid vectors having a polyoma virus origin of replication. A method to obtain a suitable cell line that expresses an acceptor molecule also is disclosed.

Affiliated with

Also associated with

Rating

A .beta.1-6 n-acetylglucosaminyltransferase and encoding dna does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with A .beta.1-6 n-acetylglucosaminyltransferase and encoding dna, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A .beta.1-6 n-acetylglucosaminyltransferase and encoding dna will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1552457