A bi-directional dual promoter complex with enhanced...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/82 (2006.01) A01H 5/00 (2006.01) A01H 5/10 (2006.01) C12N 5/14 (2006.01)

Patent

CA 2443266

The present invention is directed to bidirectional promoter complexes that are effective for enhancing transcriptional activity of transgenes. The bidirectional promoters of the invention include a modified enhancer region with at least two core promoters on either side of the modified enhancer in a divergent orientation.

L'invention se rapporte à des complexes promoteurs bidirectionnels efficaces dans l'amélioration de l'activité transcriptionnelle des transgènes. Les promoteurs bidirectionnels de cette invention renferment une région d'amplification modifiée présentant au moins deux promoteurs principaux sur chaque côté de l'amplificateur modifié dans une orientation divergente.

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