A bioassay and peptides for use therein

Details A bioassay and peptides for use therein A bioassay and peptides for use therein

C - Chemistry, Metallurgy

07

K

C07K 14/35 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 16/12 (2006.01) C12N 15/31 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2634638

The invention provides a bioassay for detection of Mycobacterium tuberculosis infection comprising artificially modified peptide subsequences of the T-cell epitope from M. tuberculosis Ag85B. Particularly preferred peptides have the form: SGGNNSPAX (SEQ ID 26), where X is Methionine (SEQ ID 18), Leucine (SEQ ID 17), Alanine (SEQ ID 15) or Valine (SEQ ID 10) and NNSPAV (SEQ ID 14). The invention also provides peptides for use in such an assay.

L'invention concerne un dosage biologique pour la détection d'une infection par Mycobacterium tuberculosis , qui comprend des sous-séquences peptidiques artificiellement modifiées de l'épitope de lymphocyte T de M. tuberculosis Ag85B. Les peptides particulièrement préférés présentent la forme: SGGNNSPAX (SEQ ID 26), X représentant méthionine (SEQ ID 18), leucine (SEQ ID 17), alanine (SEQ ID 15) ou valine (SEQ ID 10) et NNSPAV (SEQ ID 14). L'invention concerne aussi les peptides utilisés dans un tel dosage.

Affiliated with

Also associated with

Rating

A bioassay and peptides for use therein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with A bioassay and peptides for use therein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A bioassay and peptides for use therein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1684645