C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G06F 19/00 (2006.01)
Patent
CA 2622050
The present invention provides the identification and combination of genes that are expressed in tumors that are responsive to a given therapeutic agent and whose combined expression can be used as an index that correlates with responsiveness to that therapeutic agent. One or more of the genes of the present invention may be used as markers (or surrogate markers) to identify tumors that are likely to be successfully treated by that agent or class of agents such as hormonal or endocrine treatment.
La présente invention concerne l'identification et la combinaison de gènes qui sont exprimés dans des tumeurs qui sont sensibles à un agent thérapeutique donné et dont l'expression combinée peut être utilisée en tant qu'indice corrélé à la sensibilité audit agent thérapeutique. Un ou plusieurs des gènes de la présente invention peuvent être utilisés en tant que marqueurs (ou marqueurs de substitution) pour identifier des tumeurs qui sont susceptibles d'être traitées avec succès par ledit agent ou ladite classe d'agents tel qu'un traitement hormonal ou endocrinien.
Anderson Keith
Hatzis Christos
Pusztai Lajos
Symmans W. Fraser
Bcf Llp
Nuvera Biosciences Inc.
The Board Of Regents Of The University Of Texas System
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