A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/216 (2006.01)
Patent
CA 2704347
The present invention relates to a cancer sensitizer comprising chlorogenic acid or a derivative thereof. In particular, the present invention relates to a cancer sensitizer comprising chlorogenic acid or a derivative thereof, which can make cancer cells sensitive to anticancer agents to increase the therapeutic effect of anticancer agents. Inaddition, thepresent invention relates to a composition for inhibiting the chemo-resistance of cancer cells, comprising chlorogenic acid or a derivative thereof in combination with a pharmaceutically acceptable carrier, an anticancer composition comprising an anticancer agent in addition to the composition, and a method for disrupting the chemo-resistance of cancer cells, comprising administration of the cancer sensitizer.
L' invention concerne un sensibilisant du cancer comprenant un acide chlorogénique ou un dérivé de celui-ci. L' invention concerne en particulier un sensibilisant du cancer comprenant un acide chlorogénique ou un dérivé de celui-ci qui peut rendre les cellules cancéreuses sensibles à des agents anticancer afin d'augmenter leur effet thérapeutique. L'invention concerne également une composition pour inhiber la chimiorésistance des cellules cancéreuses, comprenant un acide chlorogénique ou un dérivé de celui-ci combiné à un excipient pharmaceutiquement acceptable, une composition anticancer comprenant un agent anticancer ajoutée à la composition et un procédé pour interrompre la chimiorésistance des cellules cancéreuses consistant à administrer sensibilisant du cancer.
National Cancer Center
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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