A carrier for hydrophobic drugs and a pharmaceutical...

Details A carrier for hydrophobic drugs and a pharmaceutical... A carrier for hydrophobic drugs and a pharmaceutical...

A - Human Necessities

61

K

A61K 47/44 (2006.01) A61K 9/48 (2006.01) A61K 47/08 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2185347

There is provided a carrier for hydrophobic drugs, and pharmaceutical compositions based thereon, which carrier comprises a digestible oil and a pharmaceutically acceptable surfactant component for dispersing the oil in vivo upon administration of the carrier, which comprises a hydrophilic surfactant, said surfactant component being such as not to substantially inhibit the in vivo lipolysis of the digestible oil.

L'invention se rapporte à un excipient pour médicaments hydrophobes, et à des compositions pharmaceutiques obtenues à partir de celui-ci. Cet excipient comprend une huile digestible et un composant tensioactif pharmaceutiquement acceptable qui permet de disperser l'huile in vivo lors de l'administration de l'excipient et qui comprend un tensio-actif hydrophile, ce composant tensioactif étant tel qu'il ne peut sensiblement pas inhiber la lipolyse in vivo de l'huile digestible.

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