A catheter lock solution comprising citrate and a paraben

A - Human Necessities – 01 – N

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Details

A01N 37/40 (2006.01) A01N 37/36 (2006.01) A01N 43/84 (2006.01) A01P 1/00 (2006.01) A61K 31/19 (2006.01) A61K 31/235 (2006.01) A61M 5/14 (2006.01) A61M 25/00 (2006.01)

Patent

CA 2597055

This invention relates to compositions , methods, devices and kits relating to the Infusion of a catheter lock Solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock Solution provided by the invention includes citrate and a paraben. The Solution preferably has a density suitable for retention of the Solution in a catheter during the lock period. Another lock Solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.

L'invention concerne des compositions, des procédés, des dispositifs et des kits relatifs à l'infusion d'une solution de rinçage pour cathéter dans un cathéter à demeure. Les compositions, les procédés, les dispositifs et les kits contribuent à réduire les effets de l'infection microbienne dans des cathéters, ainsi que l'occlusion des cathéters. Une solution de rinçage selon l'invention comprend du citrate et un parahydroxybenzoate. La solution présente de préférence une densité convenant pour la rétention de la solution dans un cathéter durant la période de rinçage. Selon une variante de l'invention, une solution de rinçage comprend du citrate, un parahydroxybenzoate et un photo-oxydant tel que, par exemple, du bleu de méthylène.

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