A coated nicotine-containing chewing gum, manufacture and...

Details A coated nicotine-containing chewing gum, manufacture and... A coated nicotine-containing chewing gum, manufacture and...

A - Human Necessities

61

K

A61K 9/68 (2006.01) A23B 4/10 (2006.01) A23G 4/00 (2006.01) A23G 4/04 (2006.01) A61K 31/465 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2449298

A coated chewing gum product for the delivering of nicotine in any form to a subject by a rapid transmucosal uptake in the oral cavity comprising at least one gum core, nicotine in any form and/or a nicotine mimicking agent, at lest one coating layer and optionally at least one or more other additive, wherein said at last one coating layer is buffered. Also contemplated is a method for the delivering of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as a method for producing said coated chewing gum and the use of the same form obtaining a quick transmucosal uptake of the nicotine in the oral cavity of a subject.

L'invention concerne un produit à base de gomme à mâcher enrobée destiné à administrer de la nicotine sous une quelconque forme à un patient par absorption transmucosale rapide dans la cavité buccale, qui comprend au moins un coeur de gomme, de la nicotine sous une quelconque forme et/ou un agent simulant la nicotine, au moins une couche d'enrobage et éventuellement au moins un ou plusieurs autres additifs. Ladite couche d'enrobage est tamponnée. L'invention concerne en outre un procédé d'administration de la nicotine sous une quelconque forme, un procédé de diminution du besoin de fumer ou de l'usage du tabac, ainsi qu'un procédé de production de ladite gomme à mâcher enrobée et son utilisation pour obtenir une absorption transmucosale rapide de la nicotine dans la cavité buccale d'un patient.

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