A combination of a pde4 inhibitor and a leukotriene...

A - Human Necessities – 61 – K

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A61K 31/47 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2427814

Bronchial and respiratory disorders are treated by the separate, sequential, or simultaneous administration of i) an amount of N-(3,5-dichloropyrid-4-yl)- cyclopropylmethoxy-4-difluoromethoxybenzamide, the pyridyl N-oxide thereof, or a pharmaceutically acceptable salt of either compound; and ii) an amount of a leukotriene antagonist, wherein the sum of the first and second amounts is a therapeutically effective amount.

On traite des troubles bronchiques et respiratoires en administrant de manière séparée, séquentielle, ou simultanée i) une quantité de N-(3,5-dichloropyrid-4-yl)-cyclopropylméthoxy-4-difluorométhoxybenzamide, de pyridyle de N-oxyde du composé, ou d'un sel pharmaceutiquement acceptable de l'un de ces composés, et ii) une quantité d'un antagoniste de leucotriène, la somme de la première et de la seconde quantité constituant une dose thérapeutiquement efficace.

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