A combination treatment

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/00 (2006.01) A61K 31/41 (2006.01) A61K 31/50 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2695822

A combination of a levosimendan compound or a pharmaceutically acceptable salt thereof and an angiotensin II receptor antagonist or an angiotensin converting enzyme (ACE) inhibitor shows synergistic effect in the prevention of stroke. Pharmaceutical compositions and medical kits comprising as a first active ingredient a levosimendan compound or a pharmaceutically acceptable salt thereof and as a second active ingredient an angiotensin II receptor antagonist or an angiotensin converting enzyme (ACE) inhibitor are provided.

Cette invention concerne une association d'un composé de levosimendan ou d'un de ses sels pharmaceutiquement acceptables et d'un antagoniste des récepteurs de l'angiotensine II ou d'un inhibiteur de l'enzyme de conversion de l'angiotensine (inhibiteur d'ACE), laquelle association présente un effet synergique dans la prévention de l'accident vasculaire cérébral. L'invention propose en outre des compositions pharmaceutiques et des trousses médicales contenant en tant que premier ingrédient actif un composé de levosimendan ou un de ses sels pharmaceutiquement acceptables et en tant que second ingrédient actif un antagoniste des récepteurs de l'angiotensine II ou un inhibiteur d'ACE.

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