A combination treatment for enhancing diuresis

Details A combination treatment for enhancing diuresis A combination treatment for enhancing diuresis

A - Human Necessities

61

K

A61K 31/50 (2006.01) A61K 31/585 (2006.01) A61K 31/635 (2006.01) A61P 7/10 (2006.01)

Patent

CA 2599575

A combination therapy for promoting diuresis in a patient comprises administering levosimendan or its active metabolite or any of their pharmaceutically acceptable salts in conjunction with a diuretic to a patient. The combination therapy provides diuretic effect also in patients who are refractory to standard diuretic therapy. The method is useful in the treatment of patients who suffer from fluid overload.

L~invention concerne une thérapie de combinaison pour améliorer la diurèse chez un patient, comprenant l~administration au patient de levosimendan ou de ses métabolites actifs ou de n~importe lequel de leurs sels pharmaceutiquement acceptables, conjointement avec un diurétique. La thérapie de combinaison produit des effets diurétiques même chez les patients réfractaires aux thérapies diurétiques standard. Cette méthode est utile pour traiter les patients souffrant de surcharge en fluide.

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