A composition based on perhydrosqualene and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/39 (2006.01) A61K 31/01 (2006.01) A61K 31/79 (2006.01)

Patent

CA 2733681

The instant invention relates to a composition based on collagen-polyvinylpyrrolidone and perhydrosqualene for filling, through intracutaneous route, minor skin depressions to improve its aspect without producing a negative immune reaction or rejection of extraneous body, to a process for preparing it and to its use for the prevention and treatment of minor skin depressions through a temporary mechanical effect to prevent thus the encapsulation of the substance, because depending, among various factors, on the time, some compositions can generate a reaction against the extraneous body deriving in an inflammation of the treated region and fibrosis. The composition of the instant invention is characterized because it is prepared at a controlled alkaline pH and forms a stable, foamless emulsion.

L'invention concerne une composition à base de collagène-polyvinylpyrrolidone et de perhydrosqualène pour remplir par voie intracutanée des dépressions mineures de la peau afin d'améliorer son aspect sans produire de réaction immunitaire négative ou de rejet de corps étranger, un procédé de préparation et d'utilisation de celle-ci dans la prévention et le traitement de dépressions mineures de la peau par un effet mécanique temporel pour éviter ainsi l'encapsulation de la substance, bien que dépendante, entre autres facteurs du temps, certaines compositions entraînant une réaction au corps étranger, dérivant en une inflammation de la zone traitée et en fibrose. La composition de l'invention a pour caractéristique de se préparer à un pH alcalin contrôlé et forme une émulsion stable et sans mousse.

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