A composition comprising an active agent dissolved in a...

A - Human Necessities – 61 – K

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A61K 47/12 (2006.01) A61K 9/02 (2006.01) A61K 9/06 (2006.01) A61K 9/14 (2006.01) A61K 9/48 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2225286

A biologically active composition comprising a solution of an active agent dissolved in a glass-forming carrier, which carrier comprises a glass-forming substance (A) containing a plasticizer (B), the amount of plasticizer preferably being selected so that the composition has a non-solid consistency. The composition can be prepared by dissolving the active agent in a melted mixture of the glass-forming substance and the plasticizer at a temperature below the decomposition temperature of said active agent. Use of the glass-forming carrier for dissolving a biologically active agent.

Composition bioactive comprenant une solution d'un principe actif dissout dans un transporteur vitrifiable qui comprend une substance vitrifiable (A) contenant un plastifiant (B). De préférence, la quantité de plastifiant est sélectionnée pour que la composition présente une consistance non solide. La composition peut être préparée en faisant dissoudre le principe actif dans un mélange fondu composé de la substance vitrifiable et du plastifiant à une température inférieure à la température de décomposition du principe en question. Utilisation du transporteur vitrifiable pour dissoudre un principe bioactif.

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