A composition for the sustained and controlled release of...

A - Human Necessities – 61 – K

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A61K 38/09 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 38/18 (2006.01) A61K 38/21 (2006.01) A61K 38/22 (2006.01) A61K 38/23 (2006.01) A61K 38/25 (2006.01) A61K 38/26 (2006.01) A61K 38/28 (2006.01) A61K 38/31 (2006.01) A61K 38/33 (2006.01) C07K 7/23 (2006.01)

Patent

CA 2074322

A composition designed for the sustained and con- trolled release of medicamentous peptide substances ha- ving the formula (I) : Ac-D-Nal-D-pClPhe-R3-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 wherein R3 is D-Pal or D-Trp. The composition is obtai- ned in the form of microspheres of a biodegradable polymeric material incorporating a water-insoluble salt of the peptide of formula (I).

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